Archive for the STEM CELLS IN THE NEWS Category

Saving Stem Cells – Banking Stem Cells – From your teeth

Posted in ALL ARTICLES, STEM CELLS IN THE NEWS with tags , , , , , , , , , , on April 7, 2009 by David Granovsky

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Saving Stem Cells – Banking Stem Cells – From your teeth

Kristin Lowman

Megan Brown is no stranger to surgery. At 10 years old, Megan had a brain tumor

Megan says, “two surgeries to get the turmor out, now, I’m fine.”

So today’s wisdom teeth removal is nearly a walk in the park for Megan and her family.

But this procedure is special, because one day, it could save her life.

Megan says, “its been a recent discovery that your wisdom teeth contain stem cells. So I’m going to bank them.”

Dr. Robert Carpenter says, “in teeth, particularly dediuous baby teeth and wisdom teeth there is a tremendous quality of stem cells.”

There are two sources of stem cells, embryonic and adult. Obtaining embryonic stem cells is quite controversial while adult stem cells can be found in many organs and tissues in the body, including your teeth.

Living stem cells in extracted teeth are usually thrown out, but now, research shows saving those cells, could help with medical treatments down the road.

Dr. Carpenter uses a service called Stem Save, to harvest the stem cells.

Stem Save also tests the viability of those cells and cryogenically freezes them until they are needed.

Dr. Carpenter says, “you’re getting your own stem cells so there is no chance for rejection, no disease, and you can personalize them for any use you need throughout your life.”

Right now, dental stem cells are being used to treat MS, Parkinson’s, even liver and heart disease. Several hundred clinical trials are also underway around the world.

In just over a year, around 200 dentists across the country are using this service alone.

For Megan and her parents, its a safety net they are glad to have.

They start up cost for the service is around $600. Thats for testing the cells and for the first year of storage.

Right now, Dr. Carpenter says the service is not covered by insurance

via Saving Stem Cells – FOX23 News – The 10 O’Clock News.

www.Stemsave.com

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Adult Stem Cells Are What Work

Posted in ALL ARTICLES, STEM CELLS IN THE NEWS with tags , , , , , , , , , on April 7, 2009 by David Granovsky

I think this Rep has been reading my blog and drinking the kool-aid! Only a few corrections to what he wrote. -dg

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Adult Stem Cells Are What Work

by Rep. J. Randy Forbes, 04/07/2009

Prof. Ian Wilmut of Edinburgh University is hardly a household name. However, most people would recognize his Nobel-Prize-winning scientific development. Prof. Wilmut was the individual who led the team that created the cloned sheep Dolly and pioneered a technique many would want to use for a type of embryonic stem-cell research. His action resulted in both uproar and applause all over the world and was instrumental in bringing the discussion of cloning and stem-cell research from the laboratory to the dinner table.

For years, the moral and ethical issue of destroying human embryos for scientific experimentation has been the biggest argument against embryonic stem-cell research.

(besides causing tumors and severe rejection issues -dg)

But now there is a new argument against embryonic stem-cell research: science.

Just recently, President Obama signed an executive order lifting the ban on the use of federal funds for embryonic stem-cell research, an act based more on politics than it was on science. (Private funding for this research has never been banned.) His action reignited the contentious issue for many individuals in the U.S. — it also ignored the miracles we’ve seen in advancing science.

Adult stem-cells are derived from umbilical cords, wisdom teeth, amniotic fluid, and various tissues, and they don’t hold the same ethical concerns that stem-cells taken from human embryos do. Over the years, adult stem cells have resulted in 73 successful treatments

(it’s up to 130+ now – dg)

for various diseases like Alzheimer’s, Type 1 Diabetes, Parkinson’s, and various forms of cancer.

A U.S. doctor, Amid (Amit – dg) Patel, has used adult stem cells to successfully treat over 1,800 patients who suffered from severe heart failure, dramatically increasing their quality of life and chances of survival. Two years ago, I met a man named Stephen Sprague, who had been treated for leukemia through the use of adult stem cells taken from umbilical cord blood. There are success stories like Dr. Patel’s and Stephen Sprague’s scattered across the globe where individuals have been treated for their diseases by adult stem cells, and the hope for future breakthroughs seems limitless. On the other hand, despite millions of dollars of research, not one — not one — embryonic stem-cell trial has resulted in the successful treatment of a human patient.

Perhaps most incredibly, though, is the fact that scientists have just recently figured out how to reprogram adult stem cells

(actually adult skin cells but they are turned into iPS and some argue that they must pass through an adult stem cell state while doing so – dg)

to the point where they function exactly like an embryonic stem cell. These cells, called induced pluripotent stem cells (iPS), can do everything an embryonic stem cell is capable of, only without having to destroy a human embryo. Because of this development, there is likely no medical benefit that can come from embryonic stem-cell research that cannot be obtained from adult stem cells.

(this is way to broad a generalization.  how can we determine what we can learn from something unless it is studied? – dg)

IPS cells also have a greater advantage because they can be derived from a person’s own cells, so a patient’s body is less likely to reject the stem-cell treatment.

(while this is true, many IPS cells are from other peoples cells.  recent iPS cells come from foreskins of other people or allogenic cells as opposed to autologous cells – dg)

Science is truly outpacing the embryonic stem-cell debate. Scientists across the world who were once advocates of this research have reversed course. They overwhelmingly say the future of stem-cell research lies in iPS cells and adult stem cells. Dr. James Thompson, known as the father of embryonic stem-cell research, has said that “it’s probably the beginning of the end for that controversy.” In fact, even the sheep-cloning Prof. Wilmut has abandoned embryonic stem-cell experimentation saying that the use of iPS cells is “extremely exciting and astonishing” and shows more promise for the future.

http://www.humanevents.com/article.php?id=31364/trackback/

Law of Magnetism DOES NOT WORK in the US

Posted in ALL ARTICLES, STEM CELLS IN THE NEWS with tags , , , , , , , , on April 6, 2009 by David Granovsky
  1. Adult stem cells are relatively smart and will go to their “designated organ” and repair what needs repairing (some “spilling” occurs).
  2. Nano technology will make them Einstein-ian.
  3. And magnets will control where they go like the slot cars I used to have as a kid.

So, the bottom line is…

you can get stem cells to go ANYWHERE YOU NEED THEM in the human body…

except for

INTO A PATIENT THAT NEEDS THEM IN THE US!

Sorry Farrah. Tough luck. -dg

stem-cell-research

Bone-repairing stem cell jab hope

Page last updated at 12:39 GMT, Monday, 6 April 2009 13:39 UK

By Michelle Roberts

It may be possible to control stem cells with a magnet

Doctors may soon be able to patch up damaged bones and joints anywhere in the body with a simple shot in the arm.

A team at Keele University is testing injectible stem cells that they say they can control with a magnet.

Once injected these immature cells can be guided to precisely where their help is needed and encouraged to grow new cartilage and bone, work on mice shows.

The aim is to treat patients with injuries and arthritis the UK National Stem Cell Network conference heard.

The ultimate aim is to repair cartilage and bone

Professor Alicia El Haj

Keele University

Professor Alicia El Haj, working with Professor John Dobson, also of Keele University, says the technology, patented by Magnecell, could be tested in humans within five years.

It would provide a way to treat disease without invasive surgery or powerful drugs.

The injection would use the patient’s own stem cells, harvested from their bone marrow.

These mesenchymal cells would be treated in the lab to give them a coating of minute magnetic particles.

Use in scans

These same magnetic nanoparticles are already approved in the US where they are routinely used as an agent to make MRI scans clearer to read.

Targeted magnetic fields could then move the cells around the body to the desired place and switch them into action without the need for drugs or other biochemical triggers.

Professor Al Haj said: “The ultimate aim is to repair cartilage and bone. We have been able to grow new bone in mice. Now we will look at whether we can repair damaged sites in goats.

“We should be able to move to human trials within five years.”

Meanwhile, experts at the University of Southampton, led by Professor Richard Oreffo, have treated four patients with hip joint problems using stem cell therapy.

The technique combines the patients own bone marrow stem cells with donor bone cells to patch-repair damaged bones that would otherwise need treatment with metal plates and pins.

They say it is only a matter of years before their method could be used routinely to treat some of the 60,000 people who fracture a hip in the UK each year.

via BBC NEWS | Health | Bone-repairing stem cell jab hope.

Groundbreaking Stem cell therapy Phase II trial on damage heart tissue treatment

Posted in ALL ARTICLES, STEM CELLS IN THE NEWS with tags , , , , , , , , , , on April 4, 2009 by David Granovsky

This is great news also…

but they have been treating MI with adult stem cells successfully in thailand, germany, china for almost 10 yrs now.  Catch UP! -dg

heart2

On March 30, Dr. Roger Gammon, a cardiologist with Austin Heart cardiology group treated the first patient in the world( a 58-year-old Central Texas man) enrolled in a groundbreaking Phase II study. It is one of the nation’s first hospitals to test the new therapy.

The stem cell treatment is administered intravenously and typically takes less than an hour to complete.

The Austin Heart Hospital is one of the 40 hospitals in the nation to conduct this groundbreaking adult stem cell trial, and they are excited enough to lead the way in this important research.

The aim of the study is to test the effectiveness and safety of  administering adult stem cells intravenously to repair damaged heart tissue after a heart attack.

patients are injected with donated adult stem cells from the bone marrow of others. The stems cells are purified by Osiris Therapeutics, Inc., which markets them as a product called Prochymal.

Prochymal is being evaluated for its ability to treat heart damage caused by a heart attack. The active ingredient in the new treatment is adult Mesenchymal Stem Cells (MSCs).  MSCs have the ability to develop into other types of cells and generate new tissue, including heart muscle.

Patients who are interested to participate in the study must receive the treatment within seven days of a heart attack.

Source: FoxBusiness

via Stem Cell Research Blog » Groundbreaking Stem cell therapy Phase II trial on damage heart tissue treatment.

Diseased Cartilage Harbors Unique Migratory Progenitor Cells

Posted in ALL ARTICLES, STEM CELLS IN THE NEWS with tags , , , , , , , , , on April 3, 2009 by David Granovsky

jointsScienceDaily (Apr. 2, 2009) — A new study finds previously unidentified fibrocartilage-forming progenitor cells in degenerating, diseased human cartilage, but not in cartilage from healthy joints. The research, published in the April 3rd issue of the journal Cell Stem Cell, provides valuable insights into the reparative potential of cartilage and may lead to development of regenerative therapies for arthritis.

Osteoarthritis (OA) is an incurable degenerative disease caused by a progressive deterioration of the cartilage that cushions and protects joints. “OA is the most common musculoskeletal disease in the elderly and is likely to be the fourth-leading cause of disability by the year 2020,” explains senior study author Dr. Nicolai Miosge from Georg August University in Goettingen, Germany. “This is our motivation for the further exploration of OA treatment options, including regenerative cell biological therapy.”…

via Diseased Cartilage Harbors Unique Migratory Progenitor Cells.

WMU News – Alumna discusses embryonic stem cell research

Posted in ALL ARTICLES, STEM CELLS IN THE NEWS with tags , , , , , , , , on April 3, 2009 by David Granovsky

I look forward to hearing how she handled the embryonic rejection issues and the tendency to form tumors. -dg

spinal-cord1

WMU News

Alumna discusses embryonic stem cell research

April 2, 2009

KALAMAZOO–Western Michigan University graduate Jacqueline Kueh, a doctoral student in England, returns to WMU to discuss her research in spinal cord repair and in embryonic stem cells at noon Wednesday, April 8, in Kirsch Auditorium of the Fetzer Center.

A doctoral candidate at the University College London Institute of Neurology, Kueh will address two separate lines of her research in “Pluripotency of Embryonic Stem Cells and New Developments in Spinal Cord Repair.”

After graduating from WMU in 2003, Kueh returned to her native Southeast Asia and did research at both the National University of Singapore, under the direction of Dr. Ariff Bongso, a pioneer in human embryonic stem cell research, and at the Genome Institute of Singapore. In 2006, she began her doctoral studies at University College London, where she works under Dr. Geoffrey Raisman, a pioneer in spinal cord repair.

Originally from Malaysia, Kueh began her undergraduate studies at Sunway College. She graduated summa cum laude from WMU with a bachelor’s degree in biomedical sciences. While at WMU, she was a Phi Kappa Phi Scholar and was one of the original Monroe-Brown Research Scholars in 2002. She also was active in the Malaysian Student Organization and worked in 2003 as a freshman orientation leader.

For more information about Kueh’s presentation, contact Dr. David Huffman at david.huffman@wmich.edu or (269) 387-2865.

Media contact: Thom Myers, (269) 387-8400, thom.myers@wmich.edu

WMU News
Office of University Relations
Western Michigan University
Kalamazoo MI 49008-5433 USA
(269) 387-8400
http://www.wmich.edu/wmu/news

via WMU News – Alumna discusses embryonic stem cell research.

Will Controversial Stem Cell Rider Derail Senate Budget vote?

Posted in ALL ARTICLES, STEM CELLS IN THE NEWS with tags , , , , , , , , , on April 2, 2009 by David Granovsky

Sen. Steve Ogden, a Republican from Texas, has potentially derailed not only government funding for embryonic stem cell research, but also has a attempted to derail President Obama's $3.6 trillion budget

Will Controversial Stem Cell Rider Derail Senate Budget vote?

Thursday, 02 Apr 2009

Jacksonville – Sen. Steve Ogden, a Republican from Texas, has potentially derailed not only government funding for embryonic stem cell research, but also has a attempted to derail President Obama’s $3.6 trillion budget. The rider states “No funds appropriated under this act shall be used in conjunction with or to support research which involves the destruction of a human embryo.”

The rider was passed by the Senate Finance Committee 6-5, with some members absent. The Senate is debating the budget and as of the time of this writing there is not news on whether it has passed with the addition of the stem cell rider.

President Obama had reversed George W. Bush’s executive order banning embryonic stem cell research. The controversial medical research involves using stem cells from embryos donated by parents who had In Vitro Fertilization and has extra embryos which otherwise would be destroyed. For many parents, donating these embryos to science makes them feel good. Others actually pay to have the embryos frozen forever, or allow them to be “adopted” by others for IVF.

Stem cells based medical research, including adult stem cells as well as embryonic stem cells are thought to hold the potential to treat or cure many diseases including Deafness, Paralysis, Diabetes, and Crohn’s Disease. When President Obama reversed Bush’s executive order, the NIH (National Institutes of Health) was given 120 days to come up with a set of guidelines for any Federal funding of embryonic stem cell research. Since these guidelines are not yet completed, no new embryonic stem cell research is specifically marked for funding in this year’s budget and this budget rider would make it impossible for any of the health agencies to make further determination of with funds allocated in this years budget.

Some of the issues the National Institute of Health will consider when writing guidelines for the use of embryonic stem cells in research are making sure the parents who donate embryos sign informed consent forms to show that they understand and approve of the research methodology. It is speculated that there may be additional language added to the guidelines restricting any embryos used to the products on fertility treatments. As well, it is expected that there be some separation set up between doctors who do fertility treatments and doctors who do stem cell research, to limit any conflict of interest.

Many in the medical and patient advocacy communities are very concerned that the budget will pass with this rider slipped in by a largely absent subcommittee. It is speculated that Sen. Ogden, who is said to be in his last term in office, is attempting to derail the Democrat’s budget vote by adding this controversial rider.

http://www.healthjackal.com/science/2009/04/02/will-controversial-stem-cell-rider-derail-senate-budget-vote/