Archive for the VICTORIES & SUCCESS STORIES Category

My “Battle With” and “Victory Over” MS, by Preston Walker- Part 2

Posted in ALL ARTICLES, VICTORIES & SUCCESS STORIES with tags , , , , , , , , , on April 7, 2009 by David Granovsky

ms-pic_multiple_sclerosis_stem_cell

In May 2008, I went for an adult stem cell treatment for my MS. My symptoms included fatigue, depression, a cognitive “cloud” and heat intolerance. The treatment consisted of 5 intrathecal injections, 5 physical therapy sessions, a mini-liposuction where they removed my stem cells from the fat and later injected them into me intravenously.

Today, nearly a year later the only symptom left is an occasional cognitive “cloud” moment. I talked to as many media outlets as would listen. You can google “Preston Walker MS” and find some of the coverage. I am a police sergeant in Fort Worth, TX and am still employed!! I am very lucky the disease was caught early. There is a great deal of hope in the treatment. I won’t say I am cured but symptom free!!

Preston Walker

Congrats Preston! You are a tribute to the power of adult stem cells to repair and heal. Thanks for the testimony!  Keep up the good work of spreading the word and let me know if there is anything I can do for you! -dg

for more on this story:

http://repairstemcell.wordpress.com/2009/03/20/stem-cell-research-talks-and-events-this-weekend/

http://donmargolis.com/blog/2009/01/stem-cell-treatment-keeps-helping-multiple-sclerosis-patient/

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My “Battle With” and “Victory Over” MS, by Preston Walker- Part 1

Posted in ALL ARTICLES, VICTORIES & SUCCESS STORIES with tags , , , , , , , , , , on April 7, 2009 by David Granovsky
ms-map-of-world-multiple-sclerosis
Stem Cell Treatment Keeps Helping Multiple Sclerosis Patient

I started following the saga of Preston Walker and Richard Humphries in June 2008, just after they had returned from Costa Rica to receive Adult Stem Cells to treat their Multiple Sclerosis.

Both men felt improvement immediately after the stem cell treatment.  And they still seem to be doing well- almost 9 months after the treatment.  They are gaining a following among Multiple Sclerosis patients who are well aware of their exploits.  Both Preston and Richard have become  role models for others suffering from Multiple Sclerosis

And now, Preston was featured on his local Fort Worth/Dallas Television Station:

In 2001, Walker was diagnosed with multiple sclerosis, suffered from chronic fatigue, and began losing the use of his legs.

“I felt like my cognition was declining at a rapid pace,” Walker said. “I really felt at the end of last year that I wouldn’t be employed any longer because the cognition just wasn’t there.”

That feeling changed after his Adult Stem Cell therapy in Costa Rica:

For the first time ever, doctors took samples of their fat, drew stem cells from it, and reinjected it.  By the second injection the results were obvious.  The men had more energy than they’d had in years.  By the end of the treatment Humphries no longer needed a cane to walk.

The fatigue and leg problems were a thing of the past for Walker.  “I don’t suffer from any of those symptoms we talked about,” he said.  “The depression, the fatigue, the cognitive cloud¦ I mean it will still raise its ugly head occasionally, but it’s nowhere near everyday and every moment of everyday like it was.”

And hearing about Preston’s story is nice enough but read this part too:

Humphries admits there were risks in being test patients for the treatment.  “If we or somebody doesn’t become a guinea pig than how can that benefit others?” Humphries asked.

Since their treatment, dozens of others have followed in their footsteps to receive the benefits of stem cell transplants.

The full news story is here.

Preston and Richard’s Multiple Sclerosis blog is here.

Stem Cell Research Helps Saves Diabetes Patient’s Leg From Amputation | Adult Stem Cell Research

Posted in ALL ARTICLES, VICTORIES & SUCCESS STORIES with tags , , , , , , , on April 6, 2009 by David Granovsky

Stem Cell Research Saves Diabetes Patient’s Leg From Amputation

Posted 6 April, 2009 in Peripheral Artery Disease |

Victory for Adult Stem Cell Research- Saves a Man’s Leg

Tom Fisher already had his right leg amputated due to complications from Diabetes and he was in danger of losing his left leg as well. However, stem cell research in the form of Adult Stem Cells has saved his leg from amputation and have healed all his ulcers and infections and gangrene bringing back his leg to 94% normal.

Stem Cell Therapy- Clinical Trial in Charleston, South Carolina

Fisher, 84 years old was treated at Roper Hospital in South Carolina where there is an ongoing randomized stem cell research trial for a stem-cell therapy to treat critical limb ischemia, a result of Peripheral Artery Disease.

From the stem cell news article:

“That was astounding,” said Dr. Jeb Hallett, medical director at the Roper St. Francis Heart and Vascular Center. “The results have been amazing.”

Of the nine area patients participating, seven still have their limbs, Hallett said.

Approximately 70-80% Success in Saving a Leg

The trial is sponsored by Harvest Technologies, a stem cell research company in Massachusetts who are also sponsoring similar studies in India and Europe.  According to Dr. Hallett, 87.5% of the Indian patients were able to keep their legs while in Europe, the results are 70% were able to keep their legs.

Without stem cell treatment, in similar cases of Peripheral Artery Disease, 80% LOSE their legs.  So, a 70-80% success rate for this Adult Stem Cell treatment is wonderful.

Stem Cell Treatment Before Pigs Fly?

What is not so wonderful is the results of the trial are not due until 2012.  Only 3-4 more years?? Are you serious?  Can’t we wait longer to use our own stem cells to heal ourselves?

Medicare is very interested in this as the price of stem cell treatment is cheaper than that of an angioplasty or bypass and thus would save them millions of dollars if approved by the FDA.

So if I understand correctly:

  1. the stem cell treatment is cheaper than other alternatives (angioplasty or bypass) for Peripheral Artery Disease,
  2. the therapy is safer and less invasive (just simple injections using a syringe of stem cells into the legs),
  3. it has no side effects because it uses your own Adult Stem Cells,
  4. and is probably 60-70% more effective than any other intervention— but it won’t be available for at least 4 more years (and that is being very optimistic).

Think how many legs will be lost in that time.  Way to Go FDA- your silly rules of treating a person’s own stem cells as a drug is costing lives and limbs.

Other People Helped by Adult Stem Cells for their Peripheral Artery Disease

Stem Cells for Peripheral Artery Disease

via Stem Cell Research Helps Saves Diabetes Patient’s Leg From Amputation | Adult Stem Cell Research.

Medical News: ACC: Stem Cell Treatment May Help Repair MI Damage – in Meeting Coverage, ACC from MedPage Today

Posted in ALL ARTICLES, VICTORIES & SUCCESS STORIES with tags , , , , , , , , , , , on April 4, 2009 by David Granovsky

This is great news from my alma mater…but they have been treating MI with adult stem cells successfully in thailand, germany, china for almost 10 yrs now.  Catch UP! -dg

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ACC: Stem Cell Treatment May Help Repair MI Damage

By Todd Neale, Staff Writer, MedPage Today, Published: April 02, 2009

Reviewed by Zalman S. Agus, MD; Emeritus Professor

University of Pennsylvania School of Medicine. Earn CME/CE credit

ORLANDO, April 2 — An infusion of autologous bone marrow progenitor cells may improve outcomes for patients who suffer a severe myocardial infarction, a phase I study suggested.

Action Points:

* Explain to interested patients that the findings come from a phase I study, which is designed to assess safety and feasibility, not efficacy.

* Note that this study was published as an abstract and presented as a poster at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal.

Patients who received the highest doses of enriched CD34+ endothelial progenitor cells in the affected vessel had increased perfusion of the infarct at six months (P=0.01), according to Arshed Quyyumi, M.D., of Emory University in Atlanta.

This is the first study to find a dose response when using enriched progenitor cells to repair damage following an MI severe enough to cause ventricular remodeling, he said at the American College of Cardiology meeting here…

via Medical News: ACC: Stem Cell Treatment May Help Repair MI Damage – in Meeting Coverage, ACC from MedPage Today.

The High Point Enterprise : Golf for a cause

Posted in ALL ARTICLES, VICTORIES & SUCCESS STORIES with tags , , , , , , , , , on April 3, 2009 by David Granovsky
Golf for a cause

BY STEVE HANF

The questions finally ended for Glenn Heer last August. Now the fun really begins.

High Point Central’s senior golfer celebrated his 18th birthday last week immersed in work for his senior project. Beset by an unknown and life-threatening immune system disorder nearly his entire life, Heer has turned to the game he loves to raise money for research that just became a whole lot more meaningful.

via The High Point Enterprise : Golf for a cause.

Profile of Glenn Heer

glenn-heer-complete1

via http://www.childrensinn.org/atf/cf/%7BFC217B38-92A0-42EF-A404-C40162F8FE8F%7D/Fall_07_News.pdf

Adult Spinal Stem Cells Reverse Paralysis in Rats

Posted in ALL ARTICLES, VICTORIES & SUCCESS STORIES with tags , , , , , , , , on April 2, 2009 by David Granovsky

rat-robotBoth the stem cell vocabulary and the scientific advancements seem to be growing at an almost logarithmic pace!

Stem Cell Acronym for the day:  epSPCs = ependymal stem/progenitor cells

Ependyma is the thin epithelial membrane lining the ventricular system of the brain and the spinal cord. Ependyma is one of the four types of neuroglia in the central nervous system. It is involved in the production of cerebrospinal fluid (CSF). wiki -dg

Injured spinal stem cells effectively differentiate into nerve cells

Publish date: Apr 1, 2009

WEDNESDAY, April 1 (HealthDay News) — Spinal stem cells taken from adult rats with an injured spinal cord are effective at differentiating into oligodendrocytes and motor neurons and can reverse paralysis when transplanted into rats with a spinal cord injury, according to a study published in the March issue of Stem Cells.

Victoria Moreno-Manzano, and colleagues from the Centro de Investigacion Principe Felipe in Valencia, Spain, studied the characteristics of ependymal stem/progenitor cells (epSPCs) from adult rats with a spinal cord injury and from uninjured adult rats. Ependymal cells line the central canal of the spinal cord and can regenerate the injured spinal cord in lower vertebrates; mammalian turnover of epSPCs declines during the postnatal period but can proliferate in response to injury, the study authors note.

The investigators found that epSPCs taken from injured rats proliferated 10 times faster in vitro than epSPCs from uninjured rats. Neurospheres derived from epSPCs from injured rats were more effective in differentiating into oligodendrocytes and functional spinal motor neurons. Transplantation of epSPCs from injured rats into a rat model of severe spinal cord contusion led to significant recovery of motor activity one week after injury, the researchers report. The transplanted cells migrated from the rostral and caudal regions of the transplant to axons in and around the lesion.

“Our findings demonstrate that modulation of endogenous epSPCs represents a viable cell-based strategy for restoring neuronal dysfunction in patients with spinal cord damage,” Moreno-Manzano and colleagues conclude.

via http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Adult-Spinal-Stem-Cells-Reverse-Paralysis-in-Rats/ArticleNewsFeed/Article/detail/591031?contextCategoryId=40148

Abstract
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A potential revolution in the treatment of tiniest heart patients « Adult Stem Cell Awareness

Posted in ALL ARTICLES, VICTORIES & SUCCESS STORIES with tags , , , , , , , , on April 1, 2009 by David Granovsky

heart-_awesome

A potential revolution in the treatment of tiniest heart patients

Filed under: Real Hope, adult stem cell awareness — benotafraid @ 1:49 pm

Having a child with a single ventricle heart, I’m always on the look-out for exciting advances in the field. This recent report from Pediatric Cardiology proposes the use of engineered autologous (made from one’s own cells) tissue as an alternative to heart transplantation and radical reconstructive surgeries for heart kids. This has been on the horizon for a long time, but now it’s appearing in field standard journals . . . “the future” is getting closer and closer every day.

Cardiac Tissue Engineering: Implications for Pediatric Heart Surgery

Received: 4 February 2009 Accepted: 26 February 2009 Published online: 25 March 2009

Abstract: Children with severe congenital malformations, such as single-ventricle anomalies, have a daunting prognosis. Heart transplantation would be a therapeutic option but is restricted due to a lack of suitable donor organs and, even in case of successful heart transplantation, lifelong immune suppression would frequently be associated with a number of serious side effects. As an alternative to heart transplantation and classical cardiac reconstructive surgery, tissue-engineered myocardium might become available to augment hypomorphic hearts and/or provide new muscle material for complex myocardial reconstruction. These potential applications of tissue engineered myocardium will, however, impose major challenges to cardiac tissue engineers as well as heart surgeons. This review will provide an overview of available cardiac tissue-engineering technologies, discuss limitations, and speculate on a potential application of tissue-engineered heart muscle in pediatric heart surgery.

And of course, adult stem cells and autologous tissues have turned out to be impressively effective for adult hearts, too: Improved exercise tolerance for angina patients, ASC heart failure trials, plus more – use our blog search button for “heart” and “cardiac”.

http://adultstemcellawareness.wordpress.com/2009/03/30/a-potential-revolution-in-the-treatment-of-tiniest-heart-patients/